Automated, modular system handles microarray processing

Amersham Biosciences has launched the Lucidea SlidePro Hybridizer, a slide processor that fully automates the hybridisation step of microarray applications. The modular system minimises manual handling, simplifying microarray experiments and improving the reliability and reproducibility of results.

‘The Lucidea SlidePro Hybridizer is the only automated system to optimise and run standard hybridisation protocols simultaneously or at staggered start times,’ says Michael Pettigrew, Vice President of Marketing, Genomics, at Amersham Biosciences. ‘Reliability and consistency of results are crucial for microarray data analysis, and the Lucidea SlidePro maximises signal and ratio uniformity to ensure reproducibility across and among slides.’

Amersham Biosciences designed the Lucidea SlidePro Hybridizer to automate slide pretreatment, non-static hybridisation, stringency washes, and slide drying. The system includes one to five modules, each containing six hybridisation chambers, and offers users the flexibility of being able to process from one to 30 slides at a time.

Individual temperature control for each chamber allows for customised process parameters for each slide. The vertical chamber design ensures efficient and active probe mixing and facilitates the reuse of probes. The multi-module protocol software enables users to run a different protocol on each module, and each module can run simultaneously or with different starting times.

Amersham Biosciences provides Lucidea SlidePro Hybridiser with optimised protocols for both cDNA and oligo microarrays using various surface chemistries and a large range of commercial slide types. The software automates all chemical and biochemical techniques used with standard microscope slides. Lucidea SlidePro is also suitable for slide processing applications such as protein arrays, in situ hybridisations and immunocytochemistry.