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Rheology of thickeners in pharmaceuticals: xanthan gum

By Anton Paar Ltd on

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Viscosity-increasing ingredients such as xanthan gum are widely used in complex products such as pharmaceuticals, creams, health-care products, food ingredients and dietary supplements. Their use is regulated by standards, such as the Pharmacopoeia (e.g. United States Pharmacopoeia and the European Pharmacopoeia). Although the applications of these ingredients are diverse, absolute and trustworthy rheological data are constantly required for the production and quality management of such products.

Measurements using a relative measuring system, such as a spindle, can only provide relative viscosity values because of the undefined gap dimension and thus an undefined shear field. Such results are only comparable when using the same measuring system at the same measuring height and constant temperature and, thus, can only give information about relative viscosity values.

By using modern rheometers with absolute measuring systems, complex structures can be investigated in diverse ways with high precision, measurements for quality control under process parameters can be made quickly, and can then be easily compared between laboratories.

Download the application report (above) from Anton Paar to learn how modern rheometers in combination with absolute measuring systems can provide absolute viscosity values.

Anton Paar Ltd

Anton Paar develops, produces and distributes highly accurate laboratory instruments and process measuring systems, and provides custom-tailored automation and robotic solutions.

Visit our website +44 (0) 1992 514 730

Anton Paar develops, produces and distributes highly accurate laboratory instruments and process measuring systems, and provides custom-tailored automation and robotic solutions.

It is the world leader in the measurement of density, concentration and CO2 and in the field of Rheometry. Other areas of specialty are: Viscometry, Polarimetry, Refractometry, Microwave Sample Preparation & Synthesis, Chemical and Mechanical Surface and Nanostructure Analysis.

With over 2200 employees at the headquarters in Graz (Austria) and the 25 sales subsidiaries worldwide, Anton Paar ensure that their products live up to their excellent reputation. The core competence of the company – high-precision production – and close contact to the scientific community form the basis for the quality of Anton Paar’s instruments.

A strong sales network in more than 110 countries guarantees customers rapid support and answers to their application and service queries.

Innovation is the basis for progress and every year Anton Paar invests more than 20 percent of the annual turnover in R&D.

Anton Paar Limited, a subsidiary of Anton Paar GmbH, provides sales, application support and service to users across the UK and Ireland.

With an office in St Albans (UK) and Dublin (Ireland) and a team of over 30 dedicated employees, Anton Paar Limited aims to provide first-class service at every stage in the customer relationship, ensuring our products live up to their excellent reputation.

Anton Paar Ltd
Unit F, The Courtyard
St Albans
AL4 0LA
UK

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