Bone regeneration

In-Depth

New Georgia Tech research points to better ways to heal and regenerate bones using microcomputed tomography (micro-CT) imaging - a process 1 million times more detailed than a traditional CT scan.

Tissue engineers can choose from a wide range of living cells, biomaterials and proteins to repair a bone defect. But finding the optimum combination requires improved methods for tracking the healing process.

New Georgia Tech research points to better ways to heal and regenerate bones using microcomputed tomography (micro-CT) imaging - a process 1 million times more detailed than a traditional CT scan. The new micro-CT scan technique simultaneously looks at both vascularization (the process by which blood vessels invade body tissues during repair) and mineralization (the process by which mineral crystals form to harden regenerating bone) by collecting three-dimensional images in vitro and in vivo.

Georgia Tech researchers used the new technique to help develop bone graft substitutes that combine the availability and structural integrity of bone allografts, or bone grafts taken from a human donor, with the better healing properties of bone autografts, or bone grafts taken from the patient.

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