Andrew Wade

3D biomaterials project takes off

News

A team of scientists from the University of Nottingham is embarking on a £6.5m research project to explore the use of 3D biomaterials.

The project, led by Prof Morgan Alexander from the university’s School of Pharmacy, will look to develop the next generation of materials for use in regenerative medicine, drug delivery, and medical devices.

“Advanced biomaterials are essential components in targeting infectious diseases and cancers,” said Prof Alexander. “Without this leap beyond 2D screening methodologies we will miss new advanced materials because they omit architecture and often poorly represent the in vivo environment.”

“We aim to move beyond the existing limited range of generic bio-resorbable polymeric drug and cell delivery agents to bespoke materials identified to function for specific applications.”

Despite recent advances in the field, the researchers believe there is still a significant information gap concerning the response of cells types to a broad range of materials. The aim of the project is to test a library of materials with various combinations of chemistry, stiffness, topography and shape, exploring how 3D biomaterials interact with certain cells.

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