Quaternary ammonium salts were used as ethylene source for the direct ethylation of benzylic amines. Simple Hofmann elimination delivers the olefin in situ avoiding the need for gaseous reagents and autoclave technology. The alkylation takes place under rhodium catalysis, requiring inert atmosphere, with exclusive selectivity for the C(sp3)-H bond.
Apprenticeship Funding Cuts to Cost Employers £214m
I had no idea the taxpayer was funding such an advanced level of education. Certainly graduates and post-graduates don´t receive comparable financial...