Low Volume Applications: Rotational Viscosity Testing of Pharmaceuticals and Cosmetics with Cone-Plate Geometries

This application report shows how pharmaceutical and cosmetic samples can be measured using the rotational viscometer ViscoQC 100/300 in combination with the PTD 100 Cone-Plate accessory and cone-plate (CPxx) measuring systems. The configuration gives the customer the chance to reduce the required sample volume for a viscosity measurement down to 0.5 mL to 2 mL. In contrast, for a typical rotational viscosity test with standard spindles, a sample volume of 500 mL is required. However, in many cases formulations are only produced in small quantities and include expensive ingredients. Moreover, cone-plate measuring systems provide absolute viscosity determinations for sophisticated and reliable measurements.

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