Why the Sample Holder and Preparation Matter in XRD:  Preferred Orientation of Pharmaceutical Samples

Aspirin and paracetamol are two of the most popular painkillers. X-ray diffraction, a common characterisation technique in research, development and quality control of such pharmaceuticals, regularly encounters problems with preferred orientation.

 

It is shown that these issues can be avoided with optimized measurement setups, sample holder selection and sample preparation.

 

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