Untethered electrode sheds light on therapeutic uses of neural stimulation

Researchers at the University of Pittsburgh have developed a method of neural stimulation that uses an untethered electrode activated by light, an advance that could mitigate damage done by implanted devices.

neural stimulation
A laser shining onto an untethered, ultrasmall carbon fiber electrode to stimulate neurons via the photoelectric effect (Pic: J. Mater. Chem. B, 2015,3, 4965-4978 - Reproduced by permission of RSC)

Neural stimulation can provide therapeutic effects in neurological disorders like Parkinson's disease, but implanted devices deteriorate over time and can cause scarring in neural tissue.

"Typically with neural stimulation, in order to maintain the connection between mind and machine, there is a transcutaneous cable from the implanted electrode inside of the brain to a controller outside of the body," said Takashi Kozai, an assistant professor of bioengineering at the university’s Swanson School of Engineering. "Movement of the brain or this tether leads to inflammation, scarring, and other negative side effects. We hope to reduce some of the damage by replacing this large cable with long wavelength light and an ultra small, untethered electrode."

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