Materials research points to safer stents and catheters

The material, which is extremely repellent to blood, could form the basis for surgical implants with lower risk of rejection by the body.

The work, published in Advanced Healthcare Materials, is a collaboration between the Colorado State University labs of Arun Kota, assistant professor of mechanical engineering and biomedical engineering; and Ketul Popat, associate professor in the same departments.

Starting with sheets of titanium, their labs grew chemically altered surfaces that act as barriers between the titanium and blood. Their teams then conducted experiments showing very low levels of platelet adhesion, a biological process that leads to blood clotting and eventual rejection of a foreign material.

A material phobic to blood might seem counterintuitive, the researchers said, as often biomedical scientists use materials philic to blood to make them biologically compatible.

"What we are doing is the exact opposite," Kota said in a statement. "We are taking a material that blood hates to come in contact with, in order to make it compatible with blood." The key innovation is that the surface is so repellent, that blood is tricked into believing there's virtually no foreign material there at all.