Technology could enhance systems for cell growth in labs

Technology that can quickly fabricate microscale 3D structures out of soft, biocompatible hydrogels has been developed at the University of California, San Diego.

According to the university, the technology could lead to better systems for growing and studying cells, including stem cells, in the laboratory.

In the longer term, the goal is to be able to print biological tissues for regenerative medicine. For example, in the future, doctors may repair the damage caused by heart attack by replacing it with tissue that came off a printer.

Reported in the journal Advanced Materials, the biofabrication technology, called dynamic optical projection stereolithography (DOPsL), was developed in the laboratory of NanoEngineering Prof Shaochen Chen.

Current fabrication techniques, such as photolithography and micro-contact printing, are limited to generating simple geometries or 2D patterns. Stereolithography is best known for its ability to print large objects such as tools and car parts.

The difference, said Chen in a statement, is in the micro- and nanoscale resolution required to print tissues that mimic nature’s fine-grained details, including blood vessels. Without the ability to print vasculature, an engineered liver or kidney, for example, is useless in regenerative medicine.

Register now to continue reading

Thanks for visiting The Engineer. You’ve now reached your monthly limit of news stories. Register for free to unlock unlimited access to all of our news coverage, as well as premium content including opinion, in-depth features and special reports.  

Benefits of registering

  • In-depth insights and coverage of key emerging trends

  • Unrestricted access to special reports throughout the year

  • Daily technology news delivered straight to your inbox